turmeric tablets prevents cancer

CURCUBEST – A novel bioavailable formulation

Curcumin, commonly called diferuloyl methane, is a hydrophobic polyphenol derived from the rhizome (turmeric) of the herb Curcuma longa which is a member of the ginger family (Zingiberaceae). Turmeric has been used traditionally for many ailments because of its wide spectrum of pharmacological activities. Curcumin is believed to be the most bioactive and soothing portion of the herb turmeric. Curcumin has antioxidant, anti-inflammatory, antiviral and antifungal actions. Studies have shown that curcumin is not toxic to humans. Turmeric (95 % curcumin) is effective in reducing post-surgical inflammation. It helps to prevent atherosclerosis by reducing the formation of bloods clumps.

Nevertheless curcumin has extensive health benefits, pharmacokinetic studies in animals have demonstrated that 40-85 percent of an oral dose of curcumin passes through the gastrointestinal tract unchanged, with most of the absorbed flavonoid being metabolized in the intestinal mucosa and liver.

CURCUBEST is a proprietary product from Vidya Herbs, with enhanced bioavailability. CURCUBEST is an organic turmeric extract with over 95 % curcuminoids and bioenhancers. At Vidya Herbs, we have evaluated the pharmacokinetics of CURCUBEST in preclinical models. Increased absorption of curcumin in the formulation prompted us to test the bioavailability in healthy human subjects. The increased bioavailability could be attributed to the non-curcuminoid components such as turmerones.

The presence of α- and aromatic turmerones significantly increases the amount of curcumin transported into the cells. α-turmerone inhibits the activity of P-gp, a drug efflux pump. Pgp have been proven to have a very important role in inhibiting efficient drug entry into the systemic circulation. P-gp pumps drug molecules back out of cells with the help of changing ATP to ADP. This can lead to drug resistance. Turmerones in CURCUBEST acts as inhibitors that might block the action of P-gp by taking away its ATP or by competing with the drug for the pump, so less curcumin is pumped out.

  

     CURCUBEST is proven to be safe upon oral consumption as evident from our toxicity studies in preclinical models. Further, during the human clinical studies, no adverse events were reported. CURCUBEST is available as per stringent quality control.  

Curcubest Benefits

 Contains curcuminoids such as curcumin (diferuloylmethane), demethoxycurcumin, and bisdemethoxycurcumin
 Free radical mediated 
 Useful against skin infections; Treat boils efficiently
 Protects skin from the damaging effects of UV B radiation
 Reduce formation of wrinkles on the skin; anti-ageing 
 Helps reducing inflammation, hepatic disorders 
 Prevents Cancer
 Works as Anti oxidants


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